Difference in canal encroachment by the fusion mass between anterior cervical discectomy and fusion with bone autograft and anterior plating, and stand-alone cage

作者：Lee Soo Eon; Chung Chun Kee^*; Kim Chi Heon

来源：Journal of Clinical Neuroscience, 2016, 29: 121-127.

DOI：10.1016/j.jocn.2015.10.039

• Adverse effects
• Cervical spine
• Discectomy
• Spinal fusion

We conducted a prospective randomized study comparing stand-alone cage and bone autograft and plate implants in anterior cervical discectomy and fusion (www.clinicaltrials.gov, NCT01011569). Our interim analysis showed autologous bone graft with plating was superior to a stand-alone cage for segmental lordosis. During this analysis, we noted a difference in canal encroachment by the fusion mass between the two fusion groups. A narrow cervical spinal canal is an important factor in the development of cervical spondylotic myelopathy, therefore this unexpected potential risk of spinal cord compression necessitated another interim analysis to investigate whether there was a difference in canal encroachment by the fusion mass between the two groups. Patients had a minimum 1 year of follow-up. The Neck Disability Index, neck and arm pain Visual Analog Scales and lateral radiographs, including bone fusion patterns, were evaluated. Twenty-seven (16 males, 11 females, mean age 54.8 years) and 31 (24 males, seven females, mean age 54.5 years) patients were in the cage and plate group, respectively. Both groups improved after surgery. Fusion began at 2.6 months and 1.3 months and finished at 6.7 months and 4.0 months in 24 (88.9%) and 28 (90.3%) patients in the cage and plate group, respectively. Encroachment into the spinal canal by the fusion mass was significantly different between the fusion types, occuring in 21 (77.8%) patients in the cage group versus six (19.4%) in the plate group (p = 0.003). There was a high incidence of spinal canal encroachment by the fusion mass in the standalone cage group, possibly limiting use in narrow spinal canals.

• 出版日期2016-7