Amphiphilic Silica/Fluoropolymer Nanoparticles: Synthesis, Tem-Responsive and Surface Properties as Protein-Resistance Coatings

作者：Huang, Hongpu; Qu, Jia; He, Ling^*

来源：Journal of Polymer Science Part A: Polymer Chemistry , 2016, 54(3): 381-393.

DOI：10.1002/pola.27785

• amphiphilic
• coatings
• nanoparticles
• protein-resistance
• silica/fluoropolymer
• surface properties
• tem-responsive

A series of amphiphilic silica/fluoropolymer nanoparticles of SiO2-g-P(PEGMA)-b-P(12FMA) were prepared by silica surface-initiating atom transfer radical polymerization (SI-ATRP) of poly(ethylene glycol) methyl ether methacrylate (PEGMA) and poly dodecafluoroheptyl methacrylate (P12FMA). Their amphiphilic behavior, lower critical solution temperature (LCST), and surface properties as protein-resistance coatings were characterized. The introduction of hydrophobic P(12FMA) block leads SiO2-g-P(PEGMA)-b-P(12FMA) to form individual spherical nanoparticles (similar to 150 nm in water and similar to 170 nm in THF solution) as P(PEGMA)-b-P(12FMA) shell grafted on SiO2 core (similar to 130 nm), to gain obvious lower LCST at 36-52 degrees C and higher thermostability at 290-320 degrees C than SiO2-g-P(PEGMA) (LCST578-90 degrees C, T-d=220 degrees C). The water-casted SiO2-g-P(PEGMA)-b-P(12FMA) films obtain much rougher surface (125.3-178.4 nm) than THF-casted films (11.5-16.9 nm) and all SiO2-g-P(PEGMA) films (26.8-31.3 nm). Therefore, the water-casted surfaces exhibit obvious higher water adsorption amount (Delta f=-494 similar to -426 Hz) and harder adsorbed layer (viscoelasticity of Delta D/Delta f=-0.28 similar to -0.36x10(-6)/Hz) than SiO2-g-P(PEGMA) films, but present loser adsorbed layer than THF-casted films (Delta D/Delta f=-0.29 similar to -0.63x10(-6)/Hz). While, the introduction of P(12FMA) segments does not show obviously reduce in the protein-repelling adsorption of SiO2-g-P(PEGMA)b-P(12FMA) films (Delta f=-15.7 similar to -22.3 Hz) compared with SiO2-g-P(PEGMA) films (Delta f=-8.3 similar to -11.3 Hz) and no obvious influence on water adsorption of ancient stone. Therefore, SiO2-g-P(PEGMA)-b-P(12FMA)is suggested to be used as protein-resistance coatings.

• 出版日期2016-2-1
• 单位西安交通大学