A novel metal-free method for the selenocyanation of aromatic ketones to afford alpha-carbonyl selenocyanates

作者:Sun, Kai*; Lv, Yunhe; Chen, Yao; Zhou, Tingting; Xing, Yanyan; Wang, Xin*
来源:Organic and Biomolecular Chemistry, 2017, 15(20): 4464-4467.
DOI:10.1039/c7ob00958e

摘要

A new method has been developed for the selenocyanation of aromatic ketones. This reaction avoids the need to use pre-prepared alpha-halo ketones, providing rapid access to alpha-carbonyl selenocyanates. We also investigated the mechanism for this reaction and found that it proceeds via sequential radical iodination and nucleophilic substitution reactions.