摘要
A new entry to the total synthesis of isocryptolepine (cryptosanguinolentine), isolated from Cryptolepis sanguinolenta, was achieved by constructing a tetracyclic ring system through a microwave-assisted tandem Curtius rearrangement and electrocyclic reaction of an aza 6 pi-electron system. The tetracyclic lactam was converted to isocryptolepine in a four-step sequence.
- 出版日期2012-6-3