An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

作者:Kwon Young Seop; Raston Nurul Hanun Ahmad; Gu Man Bock*
来源:Chemical communications, 2014, 50(1): 40-42.
DOI:10.1039/c3cc47108j

摘要

A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

  • 出版日期2014