An implantable optical blood pressure sensor based on pulse transit time

作者：Fiala Jens^*; Bingger Philipp; Ruh Dominic; Foerster Katharina; Heilmann Claudia; Beyersdorf Friedhelm; Zappe Hans; Seifert Andreas

来源：Biomedical Microdevices, 2013, 15(1): 73-81.

DOI：10.1007/s10544-012-9689-9

• Optical sensors
• Photoplethysmography
• Blood pressure
• Implantable sensors
• Pulse transit time
• Long-term monitoring

An implantable sensor system for long-term monitoring of blood pressure is realized by taking advantage of the correlation between pulse transit time and blood pressure. The highly integrated implantable sensor module, fabricated using MEMS technologies, uses 8 light emitting diodes (LEDs) and a photodetector on chip level. The sensor is applied to large blood vessels, such as the carotid or femoral arteries, and allows extravascular measurement of highly-resolved photoplethysmograms. In addition, spectrophotometric approaches allow measurement of hemoglobin derivatives. For the calibration of blood pressure measurements, the sensor system has been successfully implemented in animal models.

• 出版日期2013-2