A hybrid material as a sorbent phase for the disposable pipette extraction technique enhances efficiency in the determination of phenolic endocrine-disrupting compounds

作者：Corazza Gabriela; Merib Josias; Magosso Herica A; Bittencourt Otavio R; Carasek Eduardo^*

来源：Journal of Chromatography A, 2017, 1513: 42-50.

DOI：10.1016/j.chroma.2017.07.050

• DPX
• Sample preparation
• Sorbent phase
• Phenolic compounds

In this study, the hybrid material 3-n-propyl(3-methylpyridinium) silsesquioxane chloride (Si3Py(+)Cl(-)) was synthesized and investigated as a novel sorbent phase for the disposable pipette extraction (DPX) technique coupled to high-performance liquid chromatography-florescence detection. This sorbent phase was characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). Aqueous samples containing the phenolic endocrine-disrupting compounds bisphenol A (BPA), 17 alpha-ethynylestradiol (EE2), 4-tert-octylphenol (4-t-OP), 4-octylphenol (4-OP) and 4-nonylphenol (4-NP) were subjected to DPX procedures and a series of optimizations was performed to determine the ideal extraction conditions using this approach. The proposed sorbent phase exhibited higher extraction efficiency than DPX-RP (reversed phase tips containing styrene-divinylbenzene), commonly used for the determination of the phenolic endocrine-disrupting-compounds under study. Satisfactory analytical performance was achieved with linear ranges from 2 to 100 mu g L-1 for 4-t-OP and 1-100 mu g L-1 for the other analytes. Limits of detection of 0.60 mu g L-1 for 4-t-OP and 0.30 mu g L-1 for other analytes, RSDs ranging from 1 to 20% and relative recoveries of 83-116% were obtained. Based on these satisfactory results, this sorbent phase represents a valuable alternative for the extraction of compounds with polar moieties in their structure.

• 出版日期2017-9-1