Dynamics of network motifs in genetic regulatory networks

作者：Ying Li^*; Zeng Rong Liu; Jian Bao Zhang

来源：Chinese Physics, 2007, 16(9): 2587-2594.

DOI：10.1088/1009-1963/16/9/015

• genetic regulatory network
• motif
• feedback loop

Network motifs hold a very important status in genetic regulatory networks. This paper aims to analyse the dynamical property of the network motifs in genetic regulatory networks. The main result we obtained is that the dynamical property of a single motif is very simple with only an asymptotically stable equilibrium point, but the combination of several motifs can make more complicated dynamical properties emerge such as limit cycles. The above-mentioned result shows that network motif is a stable substructure in genetic regulatory networks while their combinations make the genetic regulatory network more complicated.

• 出版日期2007-9
• 单位上海大学