Different frequencies of electroacupuncture and semen coicis decrease glial fibrillary acidic protein expression in rats with hemisection spinal cord injury

作者：Hou, Chunguang; Li, Zhongzheng; Guo, Yi; Guo, Yongming^*; Liu, Yangyang; Wang, Chao; Torao, Ishida

来源：Neural Regeneration Research, 2011, 6(24): 1870-1875.

DOI：10.3969/j.issn.1673-5374.2011.24.006

• electroacupuncture
• semen coicis
• hemisection spinal cord injury
• traditional Chinese medicine
• neural regeneration

This study established the following groups of rats: a normal group, a sham surgery group, a spinal cord injury model group, a low-frequency electroacupuncture group, a high-frequency electroacupuncture group and a semen coicis group. In all but the normal and sham surgery groups, the left half of T(10) was transected. Four hours after model induction, 5-Hz and 100-Hz electroacupuncture were used to stimulate the acupoints Huantiao (GB 30), Zusanli (ST 36), Zhiyang (DU 9) and Xuanshu (DU 5), or crude extract from semen coicis was intraperitoneally injected, for 8 consecutive weeks. The results indicated that electroacupuncture stimulation and intraperitoneal injection of semen coicis improved the morphology of spinal cord tissue, promoted the recovery of motion-evoked potentials, suppressed glial fibrillary acidic protein expression, and ameliorated motor function in rats with hemisection spinal cord injury. The effects of high-frequency (100 Hz) electroacupuncture and semen coicis were significant.

• 出版日期2011-8-25
• 单位天津中医药大学