Proteoglycans specify Sonic Hedgehog effect

作者:Vaillant Catherine*; Monard Denis
来源:Nature Neuroscience, 2009, 12(4): 371-372.
DOI:10.1038/nn0409-371

摘要

How can the multifunctional factor Sonic Hedgehog (SHH) elicit specific responses from its target cells? A study now pinpoints proteoglycans as crucial anchors and modulators of SHH signaling, eliciting a proliferation response.

  • 出版日期2009-4

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