科研之友
微信
新浪微博
Facebook
分享链接
摘要
The aim of this work was to compare the distribution of Cs-137 in organisms after chronic ingestion following different schedules. Rats were contaminated through drinking water containing 6,500 Bq L-1 of Cs-137, starting either at birth, at weaning, or upon reaching adult age (13 wk). Animals were then sacrificed after different durations of ingestion. Cs-137 content of organs and excreta were determined by gamma counting. A slight decrease in Cs-137 elimination through urine was observed according to the age of animals. All organs tested showed similar Cs-137 content, with the exception of striated muscles and the thyroid at certain ages, which showed the highest accumulation of Cs-137. The lowest Cs-137 concentration was found in the blood, which acts as a transfer compartment after absorption in the intestine. Substructures of the central nervous system showed a homogeneous level of Cs-137 accumulation, except for the olfactive bulbs. In these structures, an increased concentration of Cs-137 was observed, suggesting a possible direct route of intake through the nasal epithelium. Overall, these results are in agreement with current models for the biokinetics of Cs-137. However, these results also suggest that the thyroid should be taken into account in future models of Cs-137 biokinetics. Health Phys. 99(1):39-48; 2010
- 出版日期2010-7
