A Genome-Wide Scan for Eysenckian Personality Dimensions in Adolescent Twin Sibships: Psychoticism, Extraversion, Neuroticism, and Lie

作者:Gillespie Nathan A*; Zhu Gu; Evans David M; Medland Sarah E; Wright Margie J; Martin Nick G
来源:Journal of Personality, 2008, 76(6): 1415-1445.
DOI:10.1111/j.1467-6494.2008.00527.x

摘要

We report the first genome-wide scan of adolescent personality. We conducted a genome-wide scan to detect linkage for measures of adolescent Psychoticism, Extraversion, Neuroticism, and Lie from the Junior Eysenck Personality Questionnaire. Data are based on 1,280 genotyped Australian adolescent twins and their siblings. The highest linkage peaks were found on chromosomes 16 and 19 for Neuroticism, on chromosomes 1, 7, 10, 13 m, and 18 for Psychoticism, and on chromosomes 2 and 3 for Extraversion.