Nonvisual Opsins and the Regulation of Peripheral Clocks by Light and Hormones

作者:Poletini Maristela O; Ramos Bruno C; Moraes Maria Nathalia; Castrucci Ana Maria L*
来源:Photochemistry and Photobiology, 2015, 91(5): 1046-1055.
DOI:10.1111/php.12494

摘要

The molecular clock machinery is conserved throughout evolution. However, how environmental cues are perceived has evolved in such a way that peripheral clocks in mammals require a variety of signals, including hormones. On the other hand, in nonmammalian cells able to directly detect light, light seems to play a major role in the synchronization of the clock. The interaction between perception of circadian light by nonvisual opsins and hormones will be discussed under the perspective of clock synchronization at the molecular level.

  • 出版日期2015-10