Antibacterial Gold Nanoparticles-Biomass Assisted Synthesis and Characterization

作者：Badwaik Vivek D; Willis Chad B; Pender Dillon S; Paripelly Rammohan; Shah Monic; Kherde Yogesh A; Vangala Lakshmisri M; Gonzalez Matthew S; Dakshinamurthy Rajalingam^*

来源：Journal of Biomedical Nanotechnology, 2013, 9(10): 1716-1723.

DOI：10.1166/jbn.2013.1666

• Biomass
• Gold Nanoparticles
• Green Synthesis
• Antibacterial Activity
• Microbiological Assay
• Propidium Iodide (PI)

Xylose is a natural monosaccharide found in biomass such as straw, pecan shells, cottonseed hulls, and corncobs. Using this monosaccharide, we report the facile, green synthesis and characterization of stable xylose encapsulated gold nanoparticles (Xyl-GNPs) with potent antibacterial activity. Xyl-GNPs were synthesized using the reduction property of xylose in an aqueous solution containing choloraurate anions carried out at room temperature and atmospheric pressure. These nanoparticles were stable and near spherical in shape with an average diameter of 15 +/- 5 nm. Microbiological assay results showed the concentration dependent antibacterial activity of these particles against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus epidermidis) bacteria. Thus the facile, environmentally friendly Xyl-GNPs have many potential applications in chemical and biomedical industries, particularly in the development of antibacterial agents in the field of biomedicine.

• 出版日期2013-10