RANKS: a flexible tool for node label ranking and classification in biological networks

作者:Valentini Giorgio*; Armano Giuliano; Frasca Marco; Lin Jianyi; Mesiti Marco; Re Matteo
来源:Bioinformatics, 2016, 32(18): 2872-2874.
DOI:10.1093/bioinformatics/btw235

摘要

RANKS is a flexible software package that can be easily applied to any bioinformatics task formalizable as ranking of nodes with respect to a property given as a label, such as automated protein function prediction, gene disease prioritization and drug repositioning. To this end RANKS provides an efficient and easy-to-use implementation of kernelized score functions, a semi-supervised algorithmic scheme embedding both local and global learning strategies for the analysis of biomolecular networks. To facilitate comparative assessment, baseline network-based methods, e.g. label propagation and random walk algorithms, have also been implemented.

  • 出版日期2016-9-15