摘要
A novel rhodamine-benzothiazole fluorescent probe L was designed and synthesized which can be selective detection of three kinds of metal ions (Hg2(+), Cr3(+) and Al3(+)), through the mechanism of fluorescence resonance energy transfer (FRET). This probe L shows good sensitivity towards Hg2(+), Cr3(+) and Al3(+) even at the sub-micromolar levels, which exhibited ratiometric fluorescence change from colorless to pink in aqueous media in a wide pH range of 510. Interestingly, the Jobs plot investigation suggested that L bounding to Hg2(+) or Al3(+) with a simple 1:1 mode and a 2:1 mode to Cr3(+) display different binding modes. Furthermore, the potential utility for biological applications was performed by fluorescence microscopic imaging in live cells. The results indicated that fluorescence probe L was a hopeful candidate for applications in the cell-imaging and safety inspection.
- 出版日期2017-12
- 单位功能有机分子化学国家重点实验室; 兰州大学