Automatic vs semi-automatic global cardiac function assessment using 64-row CT

作者：Greupner J; Zimmermann E; Hamm B; Dewey M^*

来源：British Journal of Radiology, 2012, 85(1015): E243-E253.

DOI：10.1259/bjr/65747000

Objective: Global cardiac function assessment using multidetector CT (MDCT) is time-consuming. Therefore we sought to compare an automatic software tool with an established semi-automatic method. %26lt;br%26gt;Methods: A total of 36 patients underwent CT with 64x0.5 mm detector collimation, and global left ventricular function was subsequently assessed by two independent blinded readers using both an automatic region-growing-based software tool (with and without manual adjustment) and an established semi-automatic software tool. We also analysed automatic motion mapping to identify end-systole. %26lt;br%26gt;Results: The time needed for assessment using the semi-automatic approach (12:12 +/- 6:19 min) was reduced by 75-85% with the automatic software tool (unadjusted, 01:34 +/- 0:29 min, adjusted, 02:53 +/- 1:19 min; both p%26lt;0.001). There was good correlation (r=0.89; p%26lt;0.001) for the ejection fraction (EF) between the adjusted automatic (58.6 +/- 14.9%) and the semi-automatic (58.0 +/- 15.3%) approaches. Also the manually adjusted automatic approach led to significantly smaller limits of agreement than the unadjusted automatic approach for end-diastolic volume (+/- 36.4 ml vs +/- 58.5 ml, p%26gt;0.05). Using motion mapping to automatically identify end-systole reduced analysis time by 95% compared with the semi-automatic approach, but showed inferior precision for EF and end-systolic volume. %26lt;br%26gt;Conclusion: Automatic function assessment using MDCT with manual adjustment shows good agreement with an established semi-automatic approach, while reducing the analysis by 75% to less than 3 min. This suggests that automatic CT function assessment with manual correction may be used for fast, comfortable and reliable evaluation of global left ventricular function.

• 出版日期2012-7