Acute toxicity of benzophenone-type UV filters and paraben preservatives to freshwater planarian, Dugesia japonica

作者：Li Mei Hui^*

来源：Toxicological and Environmental Chemistry, 2012, 94(3): 566-573.

DOI：10.1080/02772248.2012.655695

• Dugesia japonica
• aquatic toxicity
• paraben
• benzophenone
• personal care and household products

Fourteen benzophenone-type UV filters and four paraben preservatives were selected to examine their acute toxicities on Dugesia japonica. The 48-h LC50 values for planarians exposed to benzophenone-type UV filters can be ranked as oxybenzone>mexenone>5-chloro-2-hydroxybenzophenone> 2,4-dihydroxybenzophenone>2-hydroxybenzophenone4dioxybenzone>benzophenone>2,2',4,4'-tetrahydroxybenzophenone>4-hydroxybenzophenone> 3-hydroxybenzophenone>4,4'-dihydroxybenzophenone>2,2'-dihydroxy-4,4'dimethoxybenzophenone>2,3,4-trihydroxybenzophenone>sulisobenzone with a range from 0.9 to 145 mgL(-1) with a similar sequence for the 96 h LC50 values, ranging from 0.5 to 77mg L-1. The 48 and 96LC(50) values for planarians exposed to paraben preservatives can be ranked as butylparaben>propylparaben>ethylparaben>methylparaben. Among all the tested chemicals, oxybenzone was the most toxic and sulisobenzone the least toxic chemical to planarian at each exposure period. Most benzophenone-type UV filters are toxic to aquatic animals with 48 h LC50 values less than 10 mgL(-1), except for 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,3,4-trihydroxybenzophenone, and sulisobenzone. Because of their common occurrence in aquatic environment, more studies on aquatic toxicities of benzophenone-type UV filters and paraben preservativs are needed to provide important information to adequately assess their ecological risk.

• 出版日期2012