An expedient approach to pyrrolo[3,2-c]quinolines via regioselective formation of the pyrrole nucleus over indoles

作者:Karkhelikar Manjusha V; Jha Rajeev R; Sridhar B; Likhar Pravin R*; Verma Akhilesh K
来源:Chemical Communications, 2014, 50(62): 8526-8528.
DOI:10.1039/c4cc02466d

摘要

An efficient approach for the synthesis of pyrrolo[3,2-c]quinolines (the core nucleus of the natural product martinellic acid) from protected 2-alkynylanilines via the regioselective formation of pyrroles followed by Heck and intramolecular Michael addition has been described.

  • 出版日期2014-8-11