Microfluidic Sorting of Stereoisomers

作者:Eichhorn Ralf*
来源:Physical Review Letters, 2010, 105(3): 034502.
DOI:10.1103/PhysRevLett.105.034502

摘要

Isomeric molecules that only differ in the spatial orientation of their constituents are called stereoisomers. We demonstrate that different stereoisomers are transported typically at different velocities in a fluid streaming through a straight microchannel. As the underlying mechanism, we identify a translation-rotation coupling in the motion of the molecules which is specific for the molecule structure. This effect can be exploited for the separation of stereoisomers, a task of immense importance in biotechnology and pharmaceutics.

  • 出版日期2010-7-14