科研之友
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摘要
Amide formation is one of the reactions that can be undertaken within the carboxyl group of oleanolie acid. A simple method for oleanolic acid anilide and toluidides synthesis is presented. The influence of the location of the methyl substituent on the reactivity of the amine group was tested and the "ortho effect" of the methyl substituent within the molecule of o-toluidine on the time of reaction was observed. The structures of the newly obtained compounds were determined by spectroscopic methods.
- 出版日期2012-4
