Microscope-based techniques to study cell adhesion and migration

作者:Roy P*; Rajfur Z; Pomorski P; Jacobson K
来源:Nature Cell Biology, 2002, 4(4): E91-E96.
DOI:10.1038/ncb0402-e91

摘要

Modern light microscopy has evolved to provide a variety of quantitative imaging techniques and also the capability to perturb structure-function relationships in living cells. These advances have been especially useful in the study of cell adhesion and migration. This review will focus on how such microscopy-based techniques can be used in situ to study molecular interactions and dynamics, to locally perturb actin-based structures and to measure the traction forces exerted by motile cells.

  • 出版日期2002-4