Oral carcinoma cuniculatum presenting with moth-eaten destruction of the mandible

作者：Zhang, Chunye; Hu, Yuhua; Tian, Zhen; Zhu, Ling; Zhang, Chenping; Li, Jiang^*

来源：Oral Surgery Oral Medicine Oral Pathology Oral Radiology, 2018, 125(4): E86-E93.

DOI：10.1016/j.oooo.2018.01.008

• SQUAMOUS-CELL CARCINOMA
• ENTITY
• VARIANT
• TONGUE

Objective. Carcinoma cuniculatum (CC) is a rare variant of squamous cell carcinoma. We describe the clinicopathologic findings in a new case. @@@ Study Design. This is a literature review and retrospective study of a case with CC. @@@ Results. The clinical and imaging findings of CC are diverse; some cases might be challenging to diagnose accurately by biopsy. This article reports a case of CC that occurred in the retromolar region with involvement of the mandible. The patient was a 39-year-old man. Clinically, the lesion manifested as an ulcerative mass in the mandibular molar region. Imaging results showed that the lesion in the jaw exhibited moth-eaten destruction without obvious expansion of the jaw bone. The postoperative pathologic examinations were consistent with CC; additionally, metastases were present in 1 level II lymph node and 1 submandibular lymph node. Left soft tissue metastasis and right cervical lymph node metastases were detected 10 and 27 months after surgery, respectively. @@@ Conclusions. CC is a rare epithelial malignant tumor and has variable clinical manifestations. The diagnosis of CC mainly depends on pathologic features. Most patients with CC have a good prognosis; only a small percentage of patients might experience lymph node metastasis.

• 出版日期2018-4
• 单位上海市口腔病防治院; 上海交通大学