AGPBSim: Gene Pyramiding Breeding in Animals from Perspective of Synthetic Biology

作者：Xu, Lingyang; Zhao, Fuping; Ren, Hangxing; Lu, Jian; Zhang, Li; Wei, Caihong; Du, Lixin^*

来源：Journal of Animal and Veterinary Advances, 2012, 11(7): 933-938.

• Breeding
• allele frequencies
• population
• architecture
• gene-pyramiding
• platform

AGPBSim (Animal Gene-Pyramiding Breeding Simulation) is an individual-based, genetical information integrated simulation program. It was developed to investigate gene-pyramiding breeding given base population sizes, initial allele frequencies and selection strategies. The process of gene-pyramiding breeding was measured using population hamming distance, superior genotype frequency and average phenotypic values. AGPBSim is high flexible at various levels: four cross schemes and three selection strategies and trait architecture using various genotype-phenotype models were integrated in gene pyramiding breeding simulation. The GUI design of AGPBSim can facilitate design of gene-pyramiding breeding strategies by performing virtual breeding simulation on this platform.

• 出版日期2012
• 单位中国农业科学院