科研之友
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摘要
BackgroundDespite recognised benefits of optimal glycaemic control in patients with type 1 diabetes mellitus (T1DM), good control is still difficult to achieve, particularly for adolescents and young adults. Recognition of factors that may assist early optimisation of glycaemic control is therefore important. AimsWe explored associations of demographic, social and behavioural factors with glycosylated haemoglobin (HbA1c) levels in participants with T1DM aged 18-25years. MethodsA cross-sectional analysis was performed on young adults attending a dedicated multidisciplinary clinic at Fremantle Hospital, Western Australia from January to August 2014. ResultsData from 93 participants were analysed. Mean age was 21.42.3years, and 39.8% of the cohort were female. Longer duration of diabetes was associated with higher HbA1c (r=0.25, P=0.04). Men had lower HbA1c than women (8.2 +/- 1.6 vs 9.2 +/- 2.0%, P=0.01). Increased frequency of clinic attendance was associated with lower HbA1c (r=-0.27, P=0.02). Those engaged in work or study had better HbA1c compared with those who were not (8.9 +/- 2.1 vs 10.5 +/- 2.1%, P=0.03). Socioeconomic disadvantage, risk-taking behaviour, insulin pump use and distance travelled to clinic were not associated with differences in HbA1c. ConclusionIn young adults with T1DM, geographical separation, socioeconomic disadvantage and risk-taking behaviours did not influence glycaemic control. Longer duration of diabetes identifies young adults at higher risk of poor control, while attendance at a multidisciplinary clinic and engagement in work or study was associated with better glycaemic control. Additional studies are warranted to clarify the role of behavioural interventions to improve diabetes management in young adults.
- 出版日期2016-3
- 单位河北医科大学
