Ultrasensitive detection of nucleic acids by template enhanced hybridization followed by rolling circle amplification and catalytic hairpin assembly

作者：Song, Weiling^*; Zhang, Qiao; Sun, Wenbo

来源：Chemical communications, 2015, 51(12): 2392-2395.

DOI：10.1039/c4cc09453k

• MEDIATED ISOTHERMAL AMPLIFICATION
• ASSISTED SIGNAL AMPLIFICATION
• ELECTROCHEMICAL DETECTION
• STRAND-DISPLACEMENT
• DNA DETECTION
• ENZYME-FREE
• MOLECULAR BEACONS
• POLYMERASE
• CIRCUITS
• STRATEGY

An ultrasensitive protocol for fluorescent detection of DNA is designed by combining the template enhanced hybridization process (TEHP) with Rolling Circle Amplification (RCA) and Catalytic Hairpin Assembly (CHA), showing a remarkable amplification efficiency.

• 出版日期2015
• 单位青岛科技大学