Autoxidation of a tetracyclic lactam and its conversion to an enantiopure tertiary alcohol

作者:Wojaczynska Elzbieta*; Turowska Tyrk Ilona
来源:Tetrahedron: Asymmetry , 2013, 24(19): 1247-1251.
DOI:10.1016/j.tetasy.2013.08.001

摘要

The reduction of chiral tetracyclic lactams 1,2 led to new functionalized derivatives 5-8 containing 3 or 5 stereogenic centers. Autoxidation of compound 5 was observed yielding an enantiopure peroxide 9, which in turn slowly converted into tertiary alcohol 10.

  • 出版日期2013-10-15

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