Efficient and Facile Synthesis of Substituted Aminothiadiazolylhydrazonoindolin-2-ones

作者:Hassan Alaa A*; Abdel Latif Fathy F; Abdel Aziz Mohamed; Mostafa Sara M; Braese Stefan; Nieger Martin
来源:Journal of Heterocyclic Chemistry, 2016, 53(2): 633-636.
DOI:10.1002/jhet.2336

摘要

New series of substituted aminothiadiazolylhydrazonoindolin-2-ones were prepared in high yields (89-94%) via the cyclocondensation of thiocarbonohydrazides (1a, 1b, 1c, 1d) with 3-(dicyanomethylene)-2-indolone in (ethanol/piperidine) at room temperature. Explanations of these conversations involve the nucleophilic addition on the dicyanomethylene carbon atom. The structures were established by spectroscopic data and single crystal X-ray crystallography.

  • 出版日期2016-3