科研之友
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摘要
Although cancer vaccines can induce tumor-specific cytotoxic CD8(+) T cells, tumors treated by vaccination often fail to regress. A study in mice provides a potential explanation for this phenomenon by showing that a peptide vaccine in a water-oil adjuvant leads to the trapping of tumor-specific CD8(+) T cells at the vaccination site, instead of promoting an effective T cell response at the tumor site (pages 465-472).
- 出版日期2013-4
