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摘要
A new concise and enantiocontrolled total synthesis of (+)-ipomeamarone (1), a well-known phytoalexin, is described. The key step involved a tetrahydrofuran ring construction from optically active furyl alcohol 5 via the pi-allyl palladium complex with a chiral phosphine ligand. This procedure was also applicable to the synthesis of (-)-ngaione (2) and its stereoisomers.
- 出版日期2014-12-5
