A Therapeutic Target for Smoking-Associated Lung Cancer

作者:Turner Nicholas C*; Seckl Michael J
来源:Science Translational Medicine, 2010, 2(62): 62ps56.
DOI:10.1126/scitranslmed.3001942

摘要

A report in this issue of Science Translational Medicine reveals that amplification of the FGFR1 gene-which encodes fibroblast growth factor receptor 1-is a major oncogenic aberration in squamous cell lung cancer. This genetic variation may represent the first relatively high-frequency therapeutic target of smoking-associated lung cancer.

  • 出版日期2010-12-15