科研之友
微信
新浪微博
Facebook
分享链接
摘要
Ugi/de-Boc/cyclization (UDC) strategy represents a "three-step, one-pot procedure", employing the Ugi multicomponent reaction utilizing one bi-functional group substrates with N-Boc-protected amino, followed by Boc-deprotection and cyclization to synthesize nitrogen-containing heterocycles. This strategy has the characteristics of rapid, efficiency, economy and structural diversity, which can be used to build libraries of complex nitrogen-containing heterocycles and has drawn much attention recently. In this paper, the research progress of UDC strategy in the synthesis of five-, six- and seven-membered heterocycles and natural products were summarized.
- 出版日期2016-6-25
- 单位首都师范大学
