Determination of typical lipophilic marine toxins in marine sediments from three coastal bays of China using liquid chromatography-tandem mass spectrometry after accelerated solvent extraction

作者：Wang Yanlong; Chen Junhui^*; Li Zhaoyong; Wang Shuai; Shi Qian; Cao Wei; Zheng Xiaoling; Sun Chengjun; Wang Xiaoru; Zheng Li

来源：Marine Pollution Bulletin, 2015, 101(2): 954-960.

DOI：10.1016/j.marpolbul.2015.10.038

• Pressurized liquid extraction
• LC-MS/MS
• Sediment
• Lipophilic marine toxins
• Okadaic acid
• Pecenotoxin-2

A method based on sample preparation by accelerated solvent extraction and analysis by liquid chromatography-tandem mass spectrometry was validated and used for determination of seven typical lipophilic marine toxins (LMTs) in marine sediment samples collected from three typical coastal bays in China. Satisfactory specificity, reproducibility (RSDs <= 14.76%), stability (RSDs <= 17.37%), recovery (78.0%-109.0%), and detection limit (3.440 pg/g-61.85 pg/g) of the developed method were achieved. The results obtained from the analysis of samples from Hangzhou Bay revealed okadaic acid as the predominant LMT with concentrations ranging from 186.0 to 280.7 pg/g. Pecenotoxin-2 was quantified in sediment samples from Laizhou Bay at the concentrations from 256.4 to 944.9 pg/g. These results suggested that the proposed method was reliable for determining the typical LMTs in marine sediments and that the sediments obtained from Hangzhou Bay, Laizhou Bay and Jiaozhou Bay were all contaminated by certain amounts of LMTs.

• 出版日期2015-12-30
• 单位国家海洋局第一海洋研究所