Aminoacyl Benzotriazolides: Versatile Reagents for the Preparation of Peptides and Their Mimetics and Conjugates

作者：Panda Siva S; Hall C Dennis; Scriven Eric; Katritzky Alan R^*

来源：Aldrichimica Acta, 2013, 46(2): 43-55.

• benzotriazole
• peptide synthesis
• peptidomimetics
• conjugates
• methodology
• coupling reagent

N-(Protected alpha-aminoacyl)benzotriazoles are efficient acylating reagents that offer many advantages in the preparation of peptides and their mimetics and conjugates. Advances in methodology, made possible by these novel reagents, have given rise to solution- and solid-phase preparative techniques for generating complex peptides and peptide conjugates, which are useful in the construction of diverse libraries of building blocks for medicinal chemistry.

• 出版日期2013