A convenient synthesis of pyrrolopyridines and 2-substituted indoles by gold-catalyzed cycloisomerization

作者：Majumdar K C^*; Samanta S; Chattopadhyay B

来源：Tetrahedron Letters, 2008, 49(50): 7213-7216.

DOI：10.1016/j.tetlet.2008.10.013

• cycloisomerization
• Pyrrolopyridine
• 2-Substituted indole
• AuCl(3)

We have developed a gold-catalyzed intramolecular cyclization of variously Substituted acetylenic amines under mild conditions, which yields pyrrolopyridines and 2-substituted indoles, quantitatively. The cycloisomerization of acetylenic amines was achieved with AuCl(3) as catalyst Without the use of base, acid or N-protecting group.

• 出版日期2008-12-8