Highly regio- and stereoselective synthesis of tricyclic frameworks using Baylis-Hillman derivatives

作者：Bakthadoss Manickain^*; Sivakumar Nagappan; Sivakumar Govindan; Murugan Gandhi

来源：Tetrahedron Letters, 2008, 49(5): 820-823.

DOI：10.1016/j.tetlet.2007.11.210

• Baylis-Hillman reaction
• intramolecular [3+2]cycloaddition
• azomethine ylides
• 1,3-dipolar cycloaddition
• tricyclic compounds

A simple and convenient synthetic route for the synthesis of tricyclic chromeno[4,3-b]pyrrolidine frameworks using Baylis-Hillman bromides involving in situ formation of an imine, decarboxylation and a [3+2] cycloaddition sequence is described.

• 出版日期2008-1-28