A Simple Synthesis of Pyrroles Catalyzed by Acidic Resin under Solvent-Free Condition

作者:Yuan Shizhen*; Li Zhen; Xu Ling
来源:Journal of Heterocyclic Chemistry, 2010, 47(2): 446-448.
DOI:10.1002/jhet.300

摘要

A simple and effective Paal-Knorr condensation of 2, 5-hexanedione with most amines has been carried out at room temperature under solvent-free condition. The pyrroles were obtained in high yields and in short reaction times.