A multitrait GWAS sheds light on insulin resistance

作者:Heid Iris M; Winkler Thomas W
来源:Nature Genetics, 2017, 49(1): 7-8.
DOI:10.1038/ng.3758

摘要

A genome-wide study of fasting insulin, HDL cholesterol and triglycerides, designed to depict insulin resistance, identified 53 independent loci associated with a limited capacity to store fat in a healthy way. The increased power of this multitrait approach provides insights into an otherwise difficult-to-grasp phenotype.

  • 出版日期2017-1