A Green Route for Synthesis of New 1,2-Naphthoquinomethane Acetonitriles in Water

作者：Villemin Didier^*; Benabdallah Mohammed; Rahmoun Nadjib; Jouannic Cyril; Choukchou Braham Noureddine; Mostefa Kara Bachir

来源：Synthetic Communications, 2010, 40(23): 3514-3521.

DOI：10.1080/00397910903457340

• Antibacterial
• cascade reaction
• 1,2-naphthoquinomethane
• water solvent

A series of new 2-(3-hydroxy-4-oxo-4H-naphthalen-1-ylidene) acetonitriles was prepared by the cascade Michael addition-elimination reaction of sodium 1,2-naphthoquinone-4-sulfonate with various substituted acetonitriles compounds in ethanol-water in presence of basic catalyst.

• 出版日期2010