A heterogeneous strong basic Mg/La mixed oxide catalyst for efficient synthesis of polyfunctionalized pyrans

作者：Babu N Seshu; Pasha Nayeem; Rao K T Venkateswara; Prasad P S Sai; Lingalah N^*

来源：Tetrahedron Letters, 2008, 49(17): 2730-2733.

DOI：10.1016/j.tetlet.2008.02.154

• pyrans
• Mg/La mixed oxide
• three component reaction
• diketo esters

An efficient synthesis of polyfunctionalized 4H-pyrans is carried out in one pot through condensation of an aldehyde, malononitrile, and an active methylenic diketo compound using a heterogeneous strong basic Mg/La mixed oxide catalyst. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst.

• 出版日期2008-4-21