A ratiometric naphthalimide sensor for live cell imaging of copper(I)

作者:Satriano Cristina; Sfrazzetto Giuseppe Trusso; Amato Maria Emanuela; Ballistreri Francesco P; Copani Agata; Giuffrida Maria Laura; Grasso Giuseppe; Pappalardo Andrea; Rizzarelli Enrico*; Tomaselli Gaetano A; Toscano Rosa Maria
来源:Chemical communications, 2013, 49(49): 5565-5567.
DOI:10.1039/c3cc42069h

摘要

A new naphthalimide derivative bearing a tetrathia-azacrown for high affinity and selective binding to Cu+ was synthesised. Copper recognition properties in solution were evaluated using H-1 NMR and fluorescence spectroscopy. Live cell imaging by confocal microscopy highlighted the capabilities of the new sensor for the two-wavelength detection of intracellular monovalent copper in neuronal cells.

  • 出版日期2013