A Concise Total Synthesis of (+/-)- and (-)-Okilactomycin D

作者:Niu Dawen; Hoye Thomas R*
来源:Organic Letters, 2012, 14(3): 828-831.
DOI:10.1021/ol203355g

摘要

The spirotetronate okilactomycin D (7) has been efficiently synthesized by a route featuring a substrate-controlled, diastereoselective (8:1) intramolecular Diels-Alder (IMDA) reaction of 11. The assigned absolute configuration of (-)-7 was confirmed.

  • 出版日期2012-2-3