科研之友
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摘要
A novel molecular beacon (MB)-type probe possessing polyamine-bearing deoxyuridine and silylated pyrene in a short stem-portion was synthesized. The probe is assumed to form a pseudo dumbbell-type structure in near physiological conditions. The fluorescent signal of the probe was efficiently quenched while the probe stays alone. On the other hand, the signal was significantly increased under the presence of the oligoDNA complementary to the loop portion.
- 出版日期2014-12-5
