Antibacterial Activity of the Alkaloid-Enriched Extract from Prosopis juliflora Pods and Its Influence on in Vitro Ruminal Digestion

作者：dos Santos Edilene T; Pereira Mara Lucia A; da Silva Camilla Flavia P G; Souza Neta Lourdes C; Geris Regina; Martins Dirceu; Santana Antonio Euzebio G; Barbosa Luiz Claudio A; Silva Heryma Giovane O; Freitas Giovana C; Figueiredo Mauro P; de Oliveira Fernando F; Batista Ronan^*

来源：International Journal of Molecular Sciences, 2013, 14(4): 8496-8516.

DOI：10.3390/ijms14048496

• antibacterial activity
• Prosopis juliflora pods
• juliprosopine (juliflorine)
• prosoflorine
• juliprosine
• in vitro ruminal digestion
• feed additives

The purpose of this study was to assess the in vitro antimicrobial activity of alkaloid-enriched extracts from Prosopis juliflora (Fabaceae) pods in order to evaluate them as feed additives for ruminants. As only the basic chloroformic extract (BCE), whose main constituents were juliprosopine (juliflorine), prosoflorine and juliprosine, showed Gram-positive antibacterial activity against Micrococcus luteus (MIC = 25 mu g/mL), Staphylococcus aureus (MIC = 50 mu g/mL) and Streptococcus mutans (MIC = 50 mu g/mL), its influence on ruminal digestion was evaluated using a semi-automated in vitro gas production technique, with monensin as the positive control. Results showed that BCE has decreased gas production as efficiently as monensin after 36 h of fermentation, revealing its positive influence on gas production during ruminal digestion. Since P. juliflora is a very affordable plant, this study points out this alkaloid enriched extract from the pods of Prosopis juliflora as a potential feed additive to decrease gas production during ruminal digestion.

• 出版日期2013-4