alpha-cyclodextrin assisted self-assembly of poly(ethylene glycol)-block-poly(N-isopropylacrylamide) in aqueous media

作者：Yuen Fanny; Tam Kam Chiu^*

来源：Journal of Applied Polymer Science, 2013, 127(6): 4785-4794.

DOI：10.1002/app.38072

• cyclodextrin
• block copolymers
• self-assembly
• inclusion complexes
• atom transfer radical polymerization

Poly(ethylene glycol)-block-poly(N-isopropylacrylamide) (PEG-b-PNIPAM) block copolymers were synthesized by atom transfer radical polymerization, and the a-cyclodextrin (a-CD) induced self-assembly characteristics of the system were elucidated. Below the lower critical solution temperature (LCST) of PNIPAM, CD threaded onto the PEG segments and induced micellization to form rod-shaped nanostructures comprising of a PEG/a-CD condensed phase and a PNIPAM shell. Increasing the temperature of system above the LCST caused the PNIPAM segments to collapse, which resulted in the dethreading of the CD.

• 出版日期2013-3-15