A Non-Enzymatic Glucose Sensor Based on Polydopamine/Cu Microparticles Self-assembled Multilayer Films

作者：Luo Ming-Rong; Wang Liang-Liang; Zhang Ya-Jing; Zhao Shuang^*

来源：Chinese Journal of Analytical Chemistry, 2016, 44(6): 882-887.

DOI：10.11895/j.issn.0253.3820.150853

• Layer-by-layer self-assembly
• Non-enzymatic sensor
• Glucose
• Electrocatalysis
• Dopamine autopolymer

A highly stable multilayer film modified glassy carbon electrode (GCE) containing polydopamine (PDA) and Cu microparticles was fabricated by layer. by. layer self. assembly technique. The fabrication process was based on the self. polymerization of dopamine and electroless deposition of Cu microparticles on PDA coating. The fabrication process of multilayer films was characterized by UV-Vis spectra. The electrochemical performance of GCE/(PDA/Cu)(n) modified electrode for glucose detection was investigated by cyclic voltammetry and amperometric current-time curve under alkaline conditions. At detection potential of 0.35 V, the GCE/(PDA/Cu) 4 modified electrode presented a linear range of 0.5-9.0 mmol/L with a detection limit of 5.8 mu mol/L (S/N = 3). Moreover, the sensitivity of the modified electrode was tunable by controlling the number of bilayers of the multilayer films. The modified electrode showed highly selective, stable and fast amperometric sensing of glucose. It was applied to determine glucose in human blood serum with satisfactory results.

• 出版日期2016-6
• 单位东北大学