科研之友
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摘要
A dual-emission nanoprobe that can sense changes in the environmental pli is designed based on the concept of pH-responsive Forster resonance energy transfer induced by the conformational transition of an associating polyelectrolyte, N-palmitoyl chitosan, bearing a donor (Cy3) or an acceptor (Cy5) moiety. We demonstrate that the developed pH-responsive nanoprobe can be used to ratiometrically image and thus discriminate the pH changes In the biological environment at different length scales.
- 出版日期2010-12
- 单位清华大学
