A distinct novel approach for the synthesis of 3-indolyl-methanamines starting from indoles, aldehydes and nitrobenzenes in water

作者：Das Biswanath^*; Kumar Jayprakash Narayan; Kumar Avula Satya; Satyalakshmi Gandham; Shinde Digambar Balaji

来源：RSC Advances, 2013, 3(34): 14308-14311.

DOI：10.1039/c3ra41131a

3-Indolyl-methanamines have efficiently been synthesized by the treatment of indoles with aldehydes and nitrobenzenes using indium in aqueous HCl at room temperature. The products are formed in excellent yields (91-98%) within a short period of time (30-45 min). Bisindolyl methanes have not been obtained under the present reaction conditions.

• 出版日期2013