Attitudes toward antipsychotic medications as a useful feature in exploring medication non-adherence in schizophrenia

作者：Samalin Ludovic^*; de Chazeron Ingrid; Blanc Olivier; Brunel Lore; Fond Guillaume; Llorca Pierre Michel

来源：Schizophrenia Research, 2016, 178(1-3): 1-5.

DOI：10.1016/j.schres.2016.09.015

• Attitudes
• Beliefs
• Necessity-concerns framework
• Adherence
• Schizophrenia
• Antipsychotic

Objective: To investigate the interest in the attitudes toward antipsychotic medication in exploring medication non-adherence.
Methods: Schizophrenic patients (N = 120) completed the Beliefs about Medicines Questionnaire and measures of medication adherence, and clinical outcomes. Comparison between four attitudinal groups and logistic regressions were performed.
Results: High level of adherence varied significantly between attitudinal groups (Accepting, 70%; Indifferent, 63%; Ambivalent, 50%; Sceptical, 14%; p < 0.001). Poor insight and psychic side effects were the most significant predictors of negative beliefs.
Conclusion: The attitudinal groups approach could facilitate the identification of patients with non-adherence and determine individual targets of interventions to improve negative beliefs.

• 出版日期2016-12