Asymmetric Tsuji-Trost substitution in 3-acetoxy-1,3-diphenylpropene under phase-transfer conditions

作者：Vasil'ev Andrei A^*; Lyubimov Sergey E; Serebryakov Edward P; Davankov Vadim A; Zlotin Sergei G

来源：Mendeleev Communications, 2012, 22(1): 39-40.

DOI：10.1016/j.mencom.2012.01.015

P*-Chiral diamidophosphite ligand-assisted Pd-catalyzed Tsuji-Trost reaction between dimethyl malonate and prochiral 3-acetoxy-1,3-diphenylpropene in organic solvents using potassium carbonate as the base affords the substitution product in quantitative yields and with enantioselectivities up to 99% ee.

• 出版日期2012-2